KIR2DL1
From NKcells.info
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Scientific snippets
Chrul et al. (2006, PMID:17047292) demonstrated that stimulation of NK cells by a mixture of IL-12 and IL-18 caused a significant increase in KIR2DL1+ and KIR2DL2+ NK cells but not in KIR3DL2+ cells, while stimulation with IL-2 increased the frequency of all three subsets.
Ligands
Antibodies
References
Chrul S, Polakowska E, Szadkowska A, Bodalski J.
Influence of Interleukin IL-2 and IL-12 + IL-18 on Surface Expression of Immunoglobulin-Like Receptors KIR2DL1, KIR2DL2, and KIR3DL2 in Natural Killer Cells.
Mediators Inflamm. 2006;2006(4):46957., PMID:17047292
Expression of KIR2DL1 on the entire NK cell population: a possible novel immunodeficiency syndrome
Roi Gazit, Ben-Zion Garty, Yehudith Monselise, Vered Hoffer, Yaron Finkelstein, Gal Markel, Gil Katz, Jacob Hanna, Hagit Achdout, Raizy Gruda, Tsufit Gonen-Gross, and Ofer Mandelboim
Blood 2004;103 1965-1966 NKref0276
Giebel S, Locatelli F, Wojnar J, Velardi A, Mina T, Giorgiani G, Krawczyk-Kulis M, Markiewicz M, Wylezol I, Holowiecki J.
Homozygosity for human leucocyte antigen-C ligands of KIR2DL1 is associated with increased risk of relapse after human leucocyte antigen-C-matched unrelated donor haematopoietic stem cell transplantation.
Br J Haematol. 2005 Nov;131(4):483-486. PMID: 16281939
