BAT3

From NKcells.info

Contents 1 Introduction 2 Ligands 3 References 4 Further Reading

Introduction

BAT3 is the long sought cellular NKp30 ligand and exhibits a novel mechanism by which a nuclear protein activates NK cells via NKp30-engagement after its release to the cell-surface and the cell environment (Pogge von Strandmann et al., ASH2006).

Ligands

• NKp30

References

Tumor Cell-Derived HLA-B-Associated Transkript 3 (BAT3) Is a Ligand for NKp30 and Activates NK Cells.
Elke Pogge von Strandmann, Venkateswara R. Simhadri, Bastian von Tresckow, Stefanie Sasse, Katrin S. Reiners, Hinrich P. Hansen, Achim Rothe, Peter Borchmann, Peter J. McKinnon, Michael Hallek, and Andreas Engert
Blood (ASH Annual Meeting Abstracts). 2006; 108(11): p. 643

Further Reading

• NKp30, NCR
• NK cell activation